MyBioSource.com's UT-A1 Antibody: ATTO 594 is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunocytochemistry, and Western Blot. The UT-A1 Antibody: ATTO 594 was generated using SLC14A2, UT-A2, and UTA as the antigen and it reacts with Mouse, and Rat.
Description
Background Info: Detects ~97 and 117kDa.
Scientific Background: UT-A1, a kidney-specific urea transporter is expressed in the renal collecting duct where it mediates trans-epithelial urea transport and is a target for regulation by vasopressin. Urea movement out of the collecting duct in the inner medulla of the kidney allows accumulation of urea in the medullary interstitium, thereby allowing maximum water reabsorption from the collecting ducts. (The antibody also recognizes a second protein from the UT-A gene driven by transcription from an alternative promoter and expressed in the thin descending limb of Henle, viz. UT-A2.) (1, 2)